Caco-2 cells are a gold standard for preclinical drug discovery, helping evaluate novel therapeutic molecules through reliable in vitro permeability assays, toxicity testing, and drug absorption predictions.
Researchers from the University of Messina published a study in the journal Antioxidants exploring the anti-inflammatory and antioxidant properties of Citrus flavanones using a Caco-2 cell-based model stimulated with interleukins.
MedTech Barcelona contributes to technical tasks by assessing the biocompatibility and adhesion properties of Caco-2 cells on nanodevices and optimizing the interface connecting nanodevices with biosamples. We also define and implement effective strategies for the exploitation and technology transfer of the StretchBio results based on our experience in the biomedical
Understanding how MDR1 and BCRP efflux transporters influence drug-transporter interactions is critical for drug development. Discover how MDCKII cells overexpressing these proteins provide valuable insights into drug permeability, interactions, and pharmacokinetics.
